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Exosome Hair Therapy vs PRP: Origin, Evidence and What We Know

Exosome products and PRP differ in origin and in how they are made. PRP comes from your own blood and has been studied more. Exosome products are not standardized. As of the FDA's 2019 notice, no exosome product was approved. Neither has been shown to be better.

Hair loss can have medical causes. See a doctor or dermatologist before starting any treatment.

Last editorial check: October 15, 2026Sources listed belowNo promises of results

The short version

Exosome products and PRP are different things. PRP comes from your own blood and has been studied more. Exosome products come from cultured cells, plants or other sources, and they are not standardized. Neither has been shown to be better than the other. A dermatologist can tell you which, if either, fits your type of hair loss.

Side by side

Exosome hair therapy

Where it comes from
Particles collected from cultured cells (fat tissue, umbilical cord and others), plants or other sources. Not from you.
How it is prepared
In a lab, by the maker. No standard method. Reviews call for batch-level quality control (PMID 41561359).
Regulatory status
As of its notice of December 6, 2019, the FDA said no exosome product was approved.
Evidence
Small studies. One placebo-controlled trial after microneedling showed no difference from saline at 12 weeks (via PMID 42756864). One placebo-controlled study of a topical serum was positive for that product and was funded in part by its technology company (PMID 40104384).
Cost
Not published yet. See the cost page for the method.

PRP

Where it comes from
Platelets concentrated from your own blood.
How it is prepared
At the clinic, from a blood draw. Preparation methods, spin settings and volumes vary widely between studies (PMID 42799286).
Regulatory status
The sources we cite do not state the regulatory status of PRP itself. The FDA says microneedling devices are not approved for delivering blood products such as PRP into the skin.
Evidence
Studied more. A 2026 review rates the evidence in pattern hair loss as moderate to strong, with randomized trials reporting gains of roughly 10 to 30 hairs per square centimetre (PMID 42465074). A 2026 review of four randomized trials with 226 patients found partial responses and could not pool results because preparations differed (PMID 42799286).
Cost
Not published yet on this site.

Exosomes or PRP for hair: which should you ask about?

Start with the cause of your thinning. If a doctor finds a cause that has its own treatment, that comes first. If you want to compare cosmetic options, ask the clinician for the evidence for your type of hair loss, what is used and how results will be measured. We do not name a winner, because the studies do not allow it.

  • What is the evidence for this option for my kind of hair loss?
  • How is the product prepared, and can you show me?
  • How many sessions, how far apart, and what is the total cost in writing?
  • How will we know if it worked?

Questions

Can exosomes and PRP be combined?

Some clinics offer both. No study among the sources we cite tests the combination against either alone for hair, so nothing here supports it.

Is PRP approved by the FDA for hair loss?

The sources we cite do not state an FDA approval of PRP for hair loss, and we do not claim one. The FDA's microneedling page says microneedling devices are not approved for delivering blood products such as PRP into the skin.

Sources

This page has not yet been reviewed by a licensed clinician. Sources are listed below. Last editorial check: October 15, 2026.

  1. FDA, Public Safety Notification on Exosome Products, December 6, 2019. Page checked October 15, 2026.
  2. FDA, Microneedling Devices, content current as of October 15, 2025. Page checked October 15, 2026.
  3. Tang et al., narrative review of extracellular vesicles for pattern hair loss, 2026 (PMID 42756864)
  4. Lee et al., literature review on exosomes in trichology, 2026 (PMID 41561359)
  5. Weir et al., double-blind placebo-controlled study of a topical serum, 2025 (PMID 40104384)
  6. Balwi and Koldas, review of add-on therapies in hair transplantation, 2026 (PMID 42465074)
  7. Garcia Prado et al., systematic review of PRP and topical minoxidil, 2026 (PMID 42799286)